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From82US$ /night
Check-in
07Feb2026Select date
Check-out
08Feb2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

Property overview

Via Cola Di Rienzo 23, Rome, Italy, 00192
-
Close to Saint Peter's Square
Great
8.3
8.1
/10
3.5
3.7
/5

Location

Hotel Twenty One is located in the Prati district, between St Peter's and the Spanish Steps, providing easy access to Rome's main attractions. It is 400 meters from the Lepanto underground station, ensuring quick public transport to the city's renowned sites. Guests can explore landmarks such as the Vatican Museums, Trevi Fountain, and Castel Sant'Angelo all within walking distance.

Dining

Bistro 21 serves an array of traditional Italian dishes crafted from high-quality ingredients. The daily buffet lunch offers a variety of Mediterranean flavors, while dinner features an extensive menu with seasonal specials. An inviting happy hour provides a diverse selection of drinks paired with appetizing snacks.

Rooms

Hotel Twenty One features 93 well-appointed rooms, including Deluxe double rooms with private terraces and Junior Suites equipped with Jacuzzis. Each room offers custom-made furniture, LCD TVs, and modern amenities designed for guest convenience. The large suites include spacious living areas and double bathrooms for added comfort.

Family Amenities

The hotel offers connected rooms for families, including two separate bathrooms to enhance convenience. Children can enjoy easy access to several cultural sites and family-friendly attractions in the vicinity. Nearby parks and attractions allow families to explore Rome's rich history together.

Transportation Options

Hotel Twenty One is conveniently accessible by train from major transport hubs in Rome. The hotel is just a 350-meter walk from Piazza Cavour and 300 meters from the Lepanto subway station. Guests arriving by car can utilize nearby highways leading directly to the city.

Highlights

Location: Halfway between St Peter's and the Spanish Steps

Rooms: Deluxe double rooms with private terraces

Dining: Bistro 21 with Mediterranean cuisine

Family Amenities: Connected rooms with two bathrooms

“”
Hotel logo
Caleb RiversEditor, ItRome
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Choose your preferred room

You'll find everything from double rooms to larger family options, often with breakfast and easy cancellation.
Twin Room
2 persons
18 m² 
2 Single beds
Shower
Heating
Triple Room
2 persons
22 m² 
3 Single beds
Shower
Heating
Double Room
2 persons
18 m² 
1 King-size bed
Shower
Heating
Deluxe Twin Room
2 persons
23 m² 
2 Single beds
Shower
Heating
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Calendar of room availability and rates

See current availability and pricing for your dates

Facilities

Amenities are designed to ensure comfort and memorable stays

General

  • Non-smoking rooms
  • Free Wi-Fi
  • On-site car park
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • Barber shop
  • Coffee shop
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre

Services

  • Paid airport shuttle
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Packed lunches
  • Special diet menus

Business

  • Fax/Photocopying

Children

  • Cots
  • Children's buffet

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Garden area
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries
  • Sink

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Dining Onsite

Experience the vibrant culinary scene at Vista, where traditional Roman flavors meet sophisticated international tastes, creating a unique dining atmosphere. Indulge in a luscious buffet offering authentic Italian dishes and an impressive selection of wines and champagne, all set in a modern, inviting space.
Twentyone Hotel Rome Restaurant photo
Twentyone Hotel Rome Restaurant photo
Twentyone Hotel Rome Restaurant photo

Vista

International, Italian
Ambiance
Modern restaurant with a warm and inviting atmosphere
Key Offerings
Daily rich buffet featuring traditional Roman and classic Italian dishes, along with a large selection of wines and champagne
Reservation
Not needed
Open daily from 11:30 to 23:30

Twentyone Hotel Location

Via Cola Di Rienzo 23, Rome, Italy, 00192
Map view
Via Cola Di Rienzo 23, Rome, Italy, 00192
Nearby
Bridge
Castel Sant'Angelo
1.1 km
Square
Piazza del Popolo
740 m
Bridge
St. Angelo Bridge
1.1 km
Church
Church of Santa Maria del Popolo
690 m
Church
Basilica of Sant' Agostino
1.0 km
Restaurants
Bistro' 21
30 m
Via Cola di Rienzo 23 Hotel Twenty One
Cantieri Bistrot
90 m
Via Cola di Rienzo 16
Le Sicilianedde
80 m
Via Cola di Rienzo
La Pinseria Prati
80 m
Via Lucrezio Caro 60
Pasticceria Sanzini
130 m
Via Valadier
VINO e FOCACCIA
140 m
Piazza Cola di Rienzo 83/A
Grotta Azzurra
210 m
Via Cicerone 62a
Quelli del bar Cicerone
170 m
Via Cicerone 68
Ristorante Visconti 2.0
220 m
Via Ennio Quirino Visconti 83
Explore Rome
Local Highlights near Twentyone Hotel
Top Attractions
Activities
Dining
Entertainment
Vatican Museums
20 minutes walking
A treasure trove of art and history, featuring the Sistine Chapel and Raphael Rooms, perfect for art enthusiasts.
St. Peter's Basilica
20 minutes walking
Renowned for its stunning architecture and historic significance, with breathtaking views from the dome.
Piazza Navona
16 minutes walking
A lively square filled with baroque architecture, fountains, and local artists, offering a vibrant atmosphere.
Pantheon
20 minutes walking
An architectural marvel with a stunning dome, it's one of Rome's best-preserved ancient buildings.
Biking along the Tiber
15 minutes walking
Rent a bike and ride along the beautiful Tiber River, ideal for both thrill-seekers and casual riders.
Yoga in the Park
12 minutes walking
Join outdoor yoga sessions at nearby parks, perfect for relaxing and rejuvenating amidst nature.
Street Food Tours
20 minutes walking
Experience Rome's culinary scene with guided street food tours showcasing local flavors and specialties.
Bistro' 21
1 minute walking
Charming bistro offering Italian classics and local wines; perfect for a casual meal with a cozy atmosphere.
Cantieri Bistrot
2 minutes walking
Modern bistro featuring fresh, seasonal ingredients with Mediterranean flair; ideal for lunch or dinner.
La Pinseria Prati
1 minute walking
Specializes in Roman-style pizza; great for a quick and satisfying meal with a warm ambiance.
Teatro Olimpico
10 minutes drive
A grand theater hosting a variety of performances, from opera to concerts; a cultural highlight in Rome.
Wine Bars in Trastevere
15 minutes drive
Vibrant wine bars in a historic district, perfect for locals and visitors to enjoy live jazz and local wines.
Piazza Navona Night Market
16 minutes walking
Open-air market with artisans and food stalls; family-friendly and perfect for evening strolls.
Local transportation
City Centre
Rome28 min  ·  2.3 km
Airports
Rome Ciampino Airport (CIA)28 min  ·  18.6 km
Roma-Fiumicino Airport (FCO)45 min  ·  29.6 km
Train
Roma San Pietro Train Station23 min  ·  1.9 km
Underground
Lepanto Metro Station5 min  ·  400 m
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Property information and rules
Check-in
from 15:00-23:59
Check-out
from 07:00-11:00
Guest Parking
Private parking is possible on site (reservation might be needed) at EUR 35 per day.
Internet
is available in for free.
Breakfast
The hotel Twentyone provides visitors with a free full breakfast. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are not allowed.
Languages
English, German, Spanish, Italian, Russian, Moldovan
Year renovated:
2009
Number of floors:
6
Number of rooms:
88
FAQs
About Twentyone Hotel
Check-in
07Feb2026Select date
Check-out
08Feb2026Select date
Rooms and Guests2 Guests, 1 Room
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