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From128US$ /night
Check-in
08Feb2026Select date
Check-out
09Feb2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

Property overview

Via Lardaria 10, Rome, Italy, 00168
-
Near the Vatican City
Great
8.4
8.0
/10
3.6
3.4
/5

Location

Hotel Sisto V is 300 meters from Gemelli Hospital, providing convenient access for medical travelers. The hotel is just minutes away from the Vatican and Rome's historic center. The nearby 'Gemelli' urban train stop offers direct routes to major monuments such as the Colosseum and Trevi Fountain.

Rooms

The hotel offers recently renovated rooms designed for comfort and relaxation. Each room is equipped with essential amenities, including satellite TV and free Wi-Fi service. These accommodations support both business and leisure travelers effectively.

Dining

Hotel Sisto V serves a rich buffet breakfast daily, providing a variety of options to kickstart the day. The courteous and qualified staff enhance the dining experience with attentive service. On-site dining ensures convenience for guests throughout their stay.

Business

The hotel offers a comfortable equipped meeting room, suitable for various business functions and events. Efficient accommodations allow for focused meetings while enjoying the proximity to major business districts in the city. The settings cater to both corporate and casual engagements.

Outdoor Area

Hotel Sisto V includes a pleasant outdoor area, where guests can relax and unwind. This outdoor setting offers shade during summer and shelter in winter, catering to year-round comfort. Guests can enjoy moments of peace in a tranquil atmosphere.

Highlights

Location: 300 meters from Gemelli Hospital

Rooms: recently renovated rooms

Dining: rich buffet for breakfast

Business: comfortable equipped meeting room

Outdoor Area: pleasant outdoor area

“”
Hotel logo
Caleb RiversEditor, ItRome
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Choose your preferred room

You'll find everything from double rooms to larger family options, often with breakfast and easy cancellation.
Economy Double Room
2 persons
11 m² 
1 Double bed
Shower
Heating
Superior Double Room Balcony
2 persons
14 m² 
1 King-size bed
Shower
Heating
Triple Room
2 persons
14 m² 
1 King-size bed
Shower
Heating
Single Room no Bidet
2 persons
11 m² 
1 Single bed
Shower
Heating
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Calendar of room availability and rates

See current availability and pricing for your dates

Facilities

Amenities are designed to ensure comfort and memorable stays

General

  • No smoking on site
  • Wi-Fi
  • On-site car park
  • Safe deposit box
  • 24-hour reception
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • Currency exchange
  • Vending machines
  • Smoke detectors
  • Fire extinguishers

Services

  • Paid airport shuttle
  • Valet parking
  • Room service
  • Car hire
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Snack bar
  • Packed lunches

Business

  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Babysitting/Child services
  • Children's menu

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Garden area
  • Leisure/ TV room
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Dressing area
  • Patio
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Parquet floor
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Dining Onsite

Hotel Sisto V Rome Restaurant photo
Hotel Sisto V Rome Restaurant photo
Hotel Sisto V Rome Restaurant photo

Hotel Sisto V Location

Via Lardaria 10, Rome, Italy, 00168
Map view
Via Lardaria 10, Rome, Italy, 00168
Nearby
Catholic University of the Sacred Heart
420 m
Pope John Paul II
510 m
Restaurants
Pizzeria Sacchetti
280 m
Via Pineta Sacchetti 450
Burger King
340 m
Via della Pineta Sacchetti 251
Bar CentoDolci
450 m
Via Bernardo Barbiellini Amidei 2
L' Altro Caffe Roma
390 m
Via Tommaso Zigliara 33/35/37 vicino ospedale Gemelli
Piso 35 PUB & Beer Bakery
490 m
Via Vittorio Montiglio 35
Cafe Marusa
570 m
Via Mosca 27
Pane & Cioccolato
680 m
Via Pietro Maffi 105
No Pizza No Party
770 m
Via Stefano Borgia 212
Mr Chicken
760 m
Via Pietro Maffi 92
Cucineria Centonovanta Trattoria
860 m
Via di Torrevecchia 190B
Caffetteria Gelateria Black'n White
890 m
Largo Millesimo 15
Explore Rome
Local Attractions and Activities
Top Attractions
Activities
Dining
Entertainment
Vatican Museums
35 minutes' walk
Home to an extensive art collection, including the Sistine Chapel, with guided tours available to enhance your visit.
St. Peter's Basilica
40 minutes' walk
Renowned for its stunning architecture and art, including Michelangelo's Pietà. Admission is free, but donations are encouraged.
Stadio Olimpico
30 minutes' walk
An iconic stadium hosting football matches and concerts, offering guests a taste of local sports culture.
Castel Sant'Angelo
45 minutes' walk
Historic fortress offering panoramic views of the city, along with exhibits on its fascinating history.
Cycling in Pineto Regional Park
15 minutes' walk
Enjoy beautiful trails and nature. Bike rentals are available nearby, making it perfect for outdoor enthusiasts.
Yoga Sessions at Nearby Studio
5 minutes' walk
Relaxing yoga classes available. Ideal for unwinding after a busy day in the city.
Pizzeria Sacchetti
4 minutes' walk
Famous for authentic Roman pizza, offering casual dining with a friendly atmosphere. Reservations recommended for peak times.
L' Altro Caffe Roma
5 minutes' walk
Cozy café specializing in Italian coffee and pastries, perfect for breakfast or a quick snack.
Piso 35 PUB & Beer Bakery
6 minutes' walk
A lively pub known for craft beers and live music. Family-friendly atmosphere with special events on weekends.
Bar CentoDolci
6 minutes' walk
Charming bar offering live jazz music nights weekly, making it a great spot for a relaxed evening out.
Local transportation
City Centre
Rome6 min  ·  4.0 km
Airports
Roma-Fiumicino Airport (FCO)45 min  ·  29.4 km
Rome Ciampino Airport (CIA)53 min  ·  35.3 km
Train
Roma San Pietro Train Station7 min  ·  4.2 km
Underground
Battistini Metro30 min  ·  2.5 km
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Property information and rules
Check-in
from 14:00-23:30
Check-out
until 11 am
Guest Parking
Private parking is possible on site (reservation might be needed) at EUR 10 per day.
Internet
Wireless internet is available in the entire hotel for free.
Breakfast
The hotel offers a full breakfast at the price of EUR 7 per person per day. 
Children & extra beds
Maximum capacity of extra beds in a room is 1. 
Pets
Pets are allowed on request.
Languages
English, German, Spanish, Italian, Russian, Ukrainian
Year renovated:
2010
Number of floors:
4
Number of rooms:
46
FAQs
About Hotel Sisto V
Check-in
08Feb2026Select date
Check-out
09Feb2026Select date
Rooms and Guests2 Guests, 1 Room
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